ProfileGDS5029 / 227458_at
TitleSW480 KRAS-mutant colorectal cancer cell line response to dual inhibition of tankyrase and MEK: time course
OrganismHomo sapiens


untreated DMSO MEK inhibitor tankyrase inhibitor tankyrase and MEK inhibitors control 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours GSM1340521 GSM1340522 GSM1340523 GSM1340524 GSM1340531 GSM1340532 GSM1340527 GSM1340528 GSM1340535 GSM1340536 GSM1340525 GSM1340526 GSM1340533 GSM1340534 GSM1340529 GSM1340530 GSM1340537 GSM1340538 60% 59% 82% 83% 68% 73% 69% 68% 56% 57% 79% 80% 63% 70% 67% 65% 57% 55% sort by protocol sort by time Gene Expression Profile
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SampleTitleValueRank
GSM1340521parental biological replicate 131.860
GSM1340522parental biological replicate 230.159
GSM1340523DMSO 4h biological replicate 127382
GSM1340524DMSO 4h biological replicate 2285.383
GSM1340531DMSO 16h biological replicate 164.268
GSM1340532DMSO 16h biological replicate 2100.273
GSM1340527MEKi 4h biological replicate 177.369
GSM1340528MEKi 4h biological replicate 263.668
GSM1340535MEKi 16h biological replicate 123.656
GSM1340536MEKi 16h biological replicate 226.557
GSM1340525TNKSi 4h biological replicate 1190.179
GSM1340526TNKSi 4h biological replicate 2207.280
GSM1340533TNKSi 16h biological replicate 140.163
GSM1340534TNKSi 16h biological replicate 27870
GSM1340529Combo 4h biological replicate 16167
GSM1340530Combo 4h biological replicate 251.665
GSM1340537Combo 16h biological replicate 128.857
GSM1340538Combo 16h biological replicate 223.155