ProfileGDS5242 / 7928766
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 43% 41% 48% 40% 82% 64% 55% 40% 71% 50% 56% 72% 67% 67% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 13.649543
GSM1248749naïve B cells CD40L/IL-21; donor 13.511641
GSM1248746naïve B cells CD40L alone; donor 24.042748
GSM1248750naïve B cells CD40L/IL-21; donor 23.636540
GSM1248747naïve B cells CD40L alone; donor 35.224282
GSM1248751naïve B cells CD40L/IL-21; donor 34.678364
GSM1248748naïve B cells CD40L alone; donor 44.266755
GSM1248752naïve B cells CD40L/IL-21; donor 43.683840
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.783771
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 14.198550
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.438256
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.828272
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.786167
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.79867