ProfileGDS5242 / 7937560
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 49% 46% 54% 51% 78% 74% 48% 50% 69% 72% 65% 66% 73% 70% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 13.932149
GSM1248749naïve B cells CD40L/IL-21; donor 13.73246
GSM1248746naïve B cells CD40L alone; donor 24.273854
GSM1248750naïve B cells CD40L/IL-21; donor 24.060351
GSM1248747naïve B cells CD40L alone; donor 35.068378
GSM1248751naïve B cells CD40L/IL-21; donor 34.984674
GSM1248748naïve B cells CD40L alone; donor 44.019648
GSM1248752naïve B cells CD40L/IL-21; donor 44.099250
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.744269
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 14.949772
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.714365
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.632766
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.981173
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.872870