ProfileGDS5242 / 7980891
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 79% 43% 86% 54% 48% 34% 82% 27% 58% 30% 74% 18% 23% 30% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 15.531979
GSM1248749naïve B cells CD40L/IL-21; donor 13.563643
GSM1248746naïve B cells CD40L alone; donor 25.627486
GSM1248750naïve B cells CD40L/IL-21; donor 24.16954
GSM1248747naïve B cells CD40L alone; donor 34.17248
GSM1248751naïve B cells CD40L/IL-21; donor 33.682134
GSM1248748naïve B cells CD40L alone; donor 45.337882
GSM1248752naïve B cells CD40L/IL-21; donor 43.123727
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.434258
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 13.475330
GSM1248754naïve B cells CD40L alone; AD-HIES pt 25.008774
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 23.197918
GSM1248755naïve B cells CD40L alone; AD-HIES pt 33.317323
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 33.538330