ProfileGDS5242 / 7982050
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 14% 7% 90% 84% 97% 97% 91% 89% 94% 89% 97% 95% 99% 98% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 12.169514
GSM1248749naïve B cells CD40L/IL-21; donor 11.51647
GSM1248746naïve B cells CD40L alone; donor 25.998190
GSM1248750naïve B cells CD40L/IL-21; donor 25.713284
GSM1248747naïve B cells CD40L alone; donor 36.915797
GSM1248751naïve B cells CD40L/IL-21; donor 36.988797
GSM1248748naïve B cells CD40L alone; donor 46.050991
GSM1248752naïve B cells CD40L/IL-21; donor 45.989889
GSM1248753naïve B cells CD40L alone; AD-HIES pt 16.07594
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 15.780389
GSM1248754naïve B cells CD40L alone; AD-HIES pt 26.964797
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 26.211995
GSM1248755naïve B cells CD40L alone; AD-HIES pt 38.236399
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 37.527598