ProfileGDS5242 / 7985786
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 37% 47% 55% 44% 76% 67% 58% 54% 65% 59% 57% 83% 79% 72% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 13.384437
GSM1248749naïve B cells CD40L/IL-21; donor 13.758947
GSM1248746naïve B cells CD40L alone; donor 24.284855
GSM1248750naïve B cells CD40L/IL-21; donor 23.813444
GSM1248747naïve B cells CD40L alone; donor 34.983776
GSM1248751naïve B cells CD40L/IL-21; donor 34.755467
GSM1248748naïve B cells CD40L alone; donor 44.336458
GSM1248752naïve B cells CD40L/IL-21; donor 44.229854
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.617365
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 14.502959
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.468557
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 25.260183
GSM1248755naïve B cells CD40L alone; AD-HIES pt 35.172379
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.928672