ProfileGDS5242 / 7998222
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 90% 92% 90% 89% 62% 83% 85% 90% 44% 64% 87% 70% 64% 83% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 16.386990
GSM1248749naïve B cells CD40L/IL-21; donor 16.787792
GSM1248746naïve B cells CD40L alone; donor 26.004290
GSM1248750naïve B cells CD40L/IL-21; donor 26.167489
GSM1248747naïve B cells CD40L alone; donor 34.559462
GSM1248751naïve B cells CD40L/IL-21; donor 35.354683
GSM1248748naïve B cells CD40L alone; donor 45.539185
GSM1248752naïve B cells CD40L/IL-21; donor 46.102390
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.058144
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 14.647164
GSM1248754naïve B cells CD40L alone; AD-HIES pt 25.63787
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.762670
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.711764
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 35.353983