ProfileGDS5242 / 8005449
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 37% 39% 47% 38% 61% 56% 47% 45% 50% 56% 67% 57% 70% 59% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 13.347237
GSM1248749naïve B cells CD40L/IL-21; donor 13.418539
GSM1248746naïve B cells CD40L alone; donor 24.029547
GSM1248750naïve B cells CD40L/IL-21; donor 23.586338
GSM1248747naïve B cells CD40L alone; donor 34.531561
GSM1248751naïve B cells CD40L/IL-21; donor 34.424356
GSM1248748naïve B cells CD40L alone; donor 44.005447
GSM1248752naïve B cells CD40L/IL-21; donor 43.880445
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.239650
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 14.410656
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.790467
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.377757
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.886170
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.52459