ProfileGDS5242 / 8005765
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 92% 97% 91% 95% 34% 33% 90% 94% 72% 89% 51% 57% 29% 38% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 16.65792
GSM1248749naïve B cells CD40L/IL-21; donor 18.082597
GSM1248746naïve B cells CD40L alone; donor 26.145191
GSM1248750naïve B cells CD40L/IL-21; donor 26.990895
GSM1248747naïve B cells CD40L alone; donor 33.76434
GSM1248751naïve B cells CD40L/IL-21; donor 33.649533
GSM1248748naïve B cells CD40L alone; donor 45.969990
GSM1248752naïve B cells CD40L/IL-21; donor 46.702594
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.828572
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 15.816289
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.277951
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.372557
GSM1248755naïve B cells CD40L alone; AD-HIES pt 33.559929
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 33.849138