ProfileGDS5242 / 8007808
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 54% 55% 62% 54% 61% 75% 56% 66% 70% 75% 74% 84% 81% 80% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 14.174754
GSM1248749naïve B cells CD40L/IL-21; donor 14.179555
GSM1248746naïve B cells CD40L alone; donor 24.559962
GSM1248750naïve B cells CD40L/IL-21; donor 24.183854
GSM1248747naïve B cells CD40L alone; donor 34.550161
GSM1248751naïve B cells CD40L/IL-21; donor 35.034575
GSM1248748naïve B cells CD40L alone; donor 44.298856
GSM1248752naïve B cells CD40L/IL-21; donor 44.698466
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.769470
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 15.075775
GSM1248754naïve B cells CD40L alone; AD-HIES pt 25.025774
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 25.292684
GSM1248755naïve B cells CD40L alone; AD-HIES pt 35.249681
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 35.255780