ProfileGDS5242 / 8077931
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 90% 87% 92% 92% 91% 90% 93% 90% 95% 93% 89% 89% 87% 91% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 16.328990
GSM1248749naïve B cells CD40L/IL-21; donor 16.214487
GSM1248746naïve B cells CD40L alone; donor 26.197392
GSM1248750naïve B cells CD40L/IL-21; donor 26.525792
GSM1248747naïve B cells CD40L alone; donor 35.729191
GSM1248751naïve B cells CD40L/IL-21; donor 35.775490
GSM1248748naïve B cells CD40L alone; donor 46.299793
GSM1248752naïve B cells CD40L/IL-21; donor 46.156590
GSM1248753naïve B cells CD40L alone; AD-HIES pt 16.342495
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 16.181293
GSM1248754naïve B cells CD40L alone; AD-HIES pt 25.758689
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 25.60589
GSM1248755naïve B cells CD40L alone; AD-HIES pt 35.527387
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 35.85991