ProfileGDS5242 / 8110990
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 42% 42% 57% 52% 66% 68% 48% 53% 70% 57% 73% 59% 79% 69% sort by individual sort by disease state sort by protocol Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 13.592742
GSM1248749naïve B cells CD40L/IL-21; donor 13.543642
GSM1248746naïve B cells CD40L alone; donor 24.368557
GSM1248750naïve B cells CD40L/IL-21; donor 24.096452
GSM1248747naïve B cells CD40L alone; donor 34.669666
GSM1248751naïve B cells CD40L/IL-21; donor 34.792168
GSM1248748naïve B cells CD40L alone; donor 44.024248
GSM1248752naïve B cells CD40L/IL-21; donor 44.199153
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.74570
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 14.448257
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.994173
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.434459
GSM1248755naïve B cells CD40L alone; AD-HIES pt 35.179679
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.83369