ProfileGDS5242 / 8176719
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 95% 95% 6% 9% 3% 6% 2% 13% 80% 76% 79% 41% 9% 59% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 17.01495
GSM1248749naïve B cells CD40L/IL-21; donor 17.290795
GSM1248746naïve B cells CD40L alone; donor 21.66256
GSM1248750naïve B cells CD40L/IL-21; donor 21.93059
GSM1248747naïve B cells CD40L alone; donor 31.58733
GSM1248751naïve B cells CD40L/IL-21; donor 31.83876
GSM1248748naïve B cells CD40L alone; donor 41.32342
GSM1248752naïve B cells CD40L/IL-21; donor 42.236613
GSM1248753naïve B cells CD40L alone; AD-HIES pt 15.112980
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 15.116676
GSM1248754naïve B cells CD40L alone; AD-HIES pt 25.209979
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 23.929541
GSM1248755naïve B cells CD40L alone; AD-HIES pt 32.36989
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.541659