ProfileGDS5268 / 1552354_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 69% 66% 72% 67% 68% 63% 56% 61% 67% 58% 67% 56% 63% 84% 60% 69% 65% 64% 58% 58% 69% 61% 55% 61% 69% 67% 71% 64% 70% 56% 67% 72% 77% 67% 71% 70% 69% 75% 70% 67% 58% 65% 70% 62% 70% 66% 67% 70% 76% 83% 67% 69% 74% 69% 68% 76% 71% 67% 74% 64% 66% 71% 75% 68% 71% 76% 76% 84% 70% 74% 74% 66% 82% 69% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a79.458269
GSM386436Untreated HCT116 cells, replicate b70.136966
GSM386437Untreated HCT116 cells, replicate d91.367772
GSM386438Untreated HCT116 cells, replicate e74.619867
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b77.208268
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d62.257163
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e48.818956
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f59.48461
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a74.041667
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b52.111758
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d74.415867
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e49.268256
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a65.092263
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c173.39884
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e56.628460
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f77.335469
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a66.386265
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c64.575864
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e52.560558
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f51.916858
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b79.327969
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c59.711561
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d47.098455
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f58.672161
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b77.538769
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c71.406267
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d80.870171
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f63.904364
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c84.015970
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d49.582756
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e73.769467
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f93.502272
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a112.94577
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b76.945867
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e86.947671
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f86.052970
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b81.578669
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c105.95375
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d85.914370
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e75.335267
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c54.130458
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d69.180965
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e88.71870
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f62.183662
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b85.207470
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d73.051866
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e74.550467
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f82.307770
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b109.02776
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c152.85783
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f71.33667
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a82.143769
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b100.47274
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d79.984169
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e77.030268
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b117.61676
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d89.956371
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a77.173967
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d102.10274
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e66.096464
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f74.449866
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a87.811671
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c108.74775
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f76.072468
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b88.124971
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e107.64376
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b109.72476
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c154.47484
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f83.460670
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c103.7574
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d97.810674
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b72.437266
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e151.58382
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f84.105469