ProfileGDS5268 / 1555865_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 29% 34% 32% 35% 33% 30% 31% 38% 32% 32% 34% 40% 31% 33% 31% 36% 29% 36% 35% 29% 36% 33% 36% 34% 39% 41% 42% 42% 39% 37% 37% 42% 34% 35% 37% 33% 40% 36% 37% 36% 38% 30% 34% 33% 34% 29% 40% 36% 34% 36% 34% 30% 31% 31% 31% 28% 25% 29% 35% 35% 29% 34% 37% 27% 34% 41% 36% 33% 33% 35% 29% 30% 44% 34% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a21.447329
GSM386436Untreated HCT116 cells, replicate b25.102234
GSM386437Untreated HCT116 cells, replicate d24.438432
GSM386438Untreated HCT116 cells, replicate e25.852535
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b24.005933
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d22.180930
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e22.594331
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f28.030838
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a23.874432
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b23.726232
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d25.318334
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e30.141940
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a23.376231
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c25.906933
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e23.076931
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f27.55236
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a22.097229
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c25.583736
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e25.419435
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f22.090229
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b27.280836
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c24.205533
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d26.193436
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f25.160734
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b29.630839
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c29.679541
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d30.676842
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f30.885442
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c29.531339
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d28.131737
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e27.362337
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f32.126342
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a26.579734
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b26.310635
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e27.643337
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f24.865933
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b30.654740
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c27.910736
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d28.181837
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e26.916236
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c28.597238
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d23.02830
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e26.310434
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f24.872633
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b25.793434
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d21.918629
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e30.254240
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f27.550936
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b25.813734
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c28.354836
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f25.295834
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a23.383630
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b23.815831
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d24.206831
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e23.652631
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b21.655928
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d20.269125
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a21.623529
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d26.868135
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e25.865935
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f22.105229
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a24.887834
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c27.987137
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f20.894427
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b26.147234
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e31.131641
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b28.390136
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c27.121233
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f24.864433
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c27.022735
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d23.168729
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b23.028730
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e35.373344
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f26.428134