ProfileGDS5268 / 1557826_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 34% 33% 39% 37% 40% 34% 34% 37% 33% 31% 38% 32% 33% 30% 36% 38% 34% 34% 33% 38% 35% 35% 34% 33% 36% 31% 35% 31% 36% 35% 37% 34% 35% 33% 43% 32% 34% 38% 38% 37% 33% 33% 34% 34% 36% 33% 35% 35% 43% 41% 38% 35% 35% 37% 37% 36% 35% 35% 37% 33% 32% 33% 39% 38% 34% 36% 38% 32% 33% 31% 37% 35% 34% 36% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a24.693934
GSM386436Untreated HCT116 cells, replicate b24.647633
GSM386437Untreated HCT116 cells, replicate d29.630439
GSM386438Untreated HCT116 cells, replicate e27.229637
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b29.770840
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d24.927834
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e24.578934
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f27.450137
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a24.793833
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b22.548631
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d27.697638
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e23.640532
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a24.840133
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c24.208830
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e26.940436
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f28.865538
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a24.959934
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c24.006834
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e24.539233
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f27.71138
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b26.000235
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c25.265135
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d24.741534
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f24.103633
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b27.550236
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c22.665931
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d25.834535
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f22.650331
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c26.948436
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d27.151535
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e27.58637
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f25.755534
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a27.355435
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b24.965333
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e32.415243
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f24.408632
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b25.885934
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c29.040638
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d28.689838
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e27.813837
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c24.481533
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d24.746633
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e26.470334
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f25.006534
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b27.413436
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d24.441533
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e25.563935
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f26.859935
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b32.662843
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c32.797441
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f27.848338
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a26.251635
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b26.265435
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d28.067837
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e27.458337
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b27.011236
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d26.876535
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a25.419235
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d28.648337
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e24.28333
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f23.714432
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a24.402933
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c29.849339
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f28.298238
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b25.985334
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e27.547636
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b29.898238
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c26.262732
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f25.318433
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c23.782631
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d28.281337
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b26.675135
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e26.61934
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f27.66336