ProfileGDS5268 / 1558338_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 19% 21% 18% 20% 18% 18% 17% 22% 20% 20% 19% 18% 18% 19% 17% 18% 13% 27% 23% 16% 18% 18% 18% 16% 20% 24% 19% 18% 20% 15% 27% 23% 34% 21% 22% 19% 14% 18% 20% 17% 19% 22% 12% 12% 13% 17% 19% 17% 24% 31% 21% 17% 20% 17% 21% 19% 20% 19% 18% 14% 17% 18% 25% 16% 30% 20% 17% 19% 24% 23% 18% 17% 17% 18% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a16.655219
GSM386436Untreated HCT116 cells, replicate b17.653121
GSM386437Untreated HCT116 cells, replicate d16.631718
GSM386438Untreated HCT116 cells, replicate e17.211620
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b16.221218
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d16.091818
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e15.59817
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f18.046822
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a17.506120
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b17.250520
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d16.633619
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e16.593518
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a16.678318
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c17.968119
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e16.096217
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f16.872218
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a14.682513
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c19.851227
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e18.444423
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f15.542116
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b16.934918
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c16.28818
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d16.180218
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f15.434816
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b18.334720
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c19.031624
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d17.247419
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f16.430718
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c17.620120
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d15.609915
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e20.605627
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f19.309923
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a26.918234
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b17.848921
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e18.265222
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f17.181119
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b14.829314
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c17.246218
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d17.3720
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e16.293817
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c16.764619
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d18.466922
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e14.483212
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f13.930312
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b14.481413
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d15.779117
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e16.723419
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f16.348617
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b19.734524
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c24.753231
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f17.928321
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a16.615217
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b17.809720
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d16.710917
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e18.190221
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b17.107519
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d17.660720
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a16.559519
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d17.141518
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e14.852914
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f15.932817
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a16.276618
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c20.234425
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f15.5116
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b23.154630
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e17.740620
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b16.895917
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c18.354219
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f19.495824
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c19.382423
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d17.112118
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b16.252117
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e16.93217
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f16.959918