ProfileGDS5268 / 1558944_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 17% 17% 31% 23% 24% 21% 23% 24% 19% 24% 23% 22% 23% 20% 23% 27% 21% 17% 23% 25% 22% 22% 16% 26% 17% 27% 21% 17% 26% 26% 22% 24% 23% 23% 20% 24% 27% 23% 31% 22% 21% 23% 26% 20% 25% 25% 19% 24% 20% 30% 24% 18% 24% 32% 19% 20% 26% 20% 37% 19% 24% 22% 33% 26% 26% 25% 24% 27% 28% 34% 17% 19% 35% 14% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a15.622217
GSM386436Untreated HCT116 cells, replicate b15.875917
GSM386437Untreated HCT116 cells, replicate d23.607331
GSM386438Untreated HCT116 cells, replicate e18.804923
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b19.00624
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d17.56721
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e18.287723
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f19.076524
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a17.234719
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b19.089824
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d18.769123
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e18.449722
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a18.855123
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c18.498920
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e19.133123
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f21.486927
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a17.610721
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c15.509917
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e18.70323
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f19.756425
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b18.692622
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c17.889322
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d15.641116
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f19.958826
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b16.731717
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c20.437927
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d18.014921
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f15.903717
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c20.338826
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d20.610826
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e18.458322
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f19.659424
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a19.543123
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b18.68123
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e17.447520
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f19.676824
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b21.258727
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c19.517423
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d23.460931
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e18.590922
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c17.812821
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d19.15423
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e21.253326
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f17.401120
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b19.980225
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d19.578625
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e16.989719
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f19.866124
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b17.707420
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c23.960430
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f19.473124
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a16.772918
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b19.640524
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d24.827232
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e17.310419
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b17.834420
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d20.88426
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a17.214520
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d28.168737
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e16.972419
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f19.037124
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a18.331522
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c25.003633
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f20.407926
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b20.901626
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e20.519625
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b20.110624
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c22.942927
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f21.779228
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c25.954634
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d16.453517
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b16.991519
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e27.225635
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f15.129814