ProfileGDS5268 / 1559458_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 21% 20% 22% 24% 18% 20% 22% 19% 24% 20% 21% 15% 24% 21% 16% 16% 18% 19% 22% 17% 20% 20% 16% 21% 12% 13% 14% 21% 23% 18% 19% 18% 25% 21% 20% 21% 23% 20% 20% 19% 20% 19% 30% 17% 20% 26% 22% 18% 22% 23% 19% 19% 25% 18% 26% 22% 21% 23% 16% 20% 21% 25% 16% 18% 19% 19% 19% 19% 19% 17% 20% 23% 20% 21% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a17.366921
GSM386436Untreated HCT116 cells, replicate b17.34420
GSM386437Untreated HCT116 cells, replicate d18.645222
GSM386438Untreated HCT116 cells, replicate e19.509424
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b16.500218
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d17.242420
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e17.937722
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f16.94219
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a19.233624
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b17.141920
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d17.869721
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e15.261215
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a19.079324
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c19.155121
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e15.842816
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f16.196416
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a16.618418
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c16.268219
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e18.096622
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f15.934317
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b17.467220
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c17.098620
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d15.495816
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f17.44721
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b14.458112
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c14.377413
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d15.30814
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f17.426521
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c18.893523
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d16.98318
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e17.122419
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f17.041718
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a20.809225
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b17.790121
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e17.373920
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f18.219421
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b19.048323
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c17.777920
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d17.285520
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e17.061819
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c17.250320
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d16.870419
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e23.666730
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f15.887917
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b17.621620
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d20.613326
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e18.427222
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f16.968518
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b18.715422
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c19.695523
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f16.839819
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a17.103619
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b20.209925
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d16.860518
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e20.783926
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b18.809422
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d18.135321
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a18.81823
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d16.196616
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e17.517620
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f17.748521
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a19.496125
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c16.158716
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f16.556418
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b17.403219
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e17.481719
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b17.427219
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c18.086419
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f17.511619
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c16.597417
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d18.050720
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b19.302223
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e17.965120
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f18.171621