ProfileGDS5268 / 1562895_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 29% 32% 33% 26% 29% 30% 31% 28% 25% 25% 34% 29% 30% 35% 31% 30% 34% 25% 28% 33% 29% 31% 33% 34% 32% 27% 32% 32% 29% 34% 31% 30% 31% 33% 32% 33% 39% 30% 34% 30% 28% 33% 34% 33% 30% 29% 32% 36% 31% 38% 32% 33% 34% 29% 27% 28% 29% 24% 29% 33% 32% 32% 37% 29% 26% 33% 31% 38% 35% 29% 28% 33% 33% 35% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a21.436329
GSM386436Untreated HCT116 cells, replicate b23.612432
GSM386437Untreated HCT116 cells, replicate d24.865133
GSM386438Untreated HCT116 cells, replicate e20.571126
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b21.692729
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d22.25630
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e22.607831
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f21.253828
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a20.203525
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b19.705925
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d25.04634
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e22.016929
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a22.682430
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c27.113535
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e23.123631
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f23.452830
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a25.173834
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c19.206925
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e21.256928
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f23.959333
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b22.499629
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c23.234831
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d24.382633
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f24.647134
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b24.636332
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c20.813327
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d23.99232
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f23.548132
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c22.189129
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d25.896534
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e22.931431
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f22.806930
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a24.589231
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b25.10133
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e24.149732
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f24.885133
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b29.912839
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c23.814430
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d25.375934
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e22.464930
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c21.572728
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d24.919333
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e26.343834
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f24.305733
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b22.848830
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d22.330829
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e23.68332
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f26.992136
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b23.458731
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c30.049538
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f24.121132
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a24.831933
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b25.952834
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d22.766229
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e21.375927
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b22.002328
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d22.676929
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a19.273924
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d22.6529
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e24.626733
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f23.786132
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a23.512832
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c27.975337
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f21.60329
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b20.984326
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e25.006533
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b24.210431
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c30.899738
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f26.556635
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c22.767929
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d22.204928
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b24.927833
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e26.18933
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f26.8935