ProfileGDS5268 / 1569325_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 58% 60% 63% 60% 60% 57% 55% 58% 60% 55% 58% 58% 58% 67% 57% 53% 58% 60% 58% 57% 60% 56% 56% 50% 61% 56% 63% 54% 62% 59% 61% 61% 65% 56% 60% 54% 55% 60% 58% 59% 52% 60% 57% 58% 61% 52% 61% 59% 69% 66% 62% 62% 64% 59% 62% 67% 61% 62% 59% 59% 56% 56% 59% 55% 64% 63% 62% 74% 59% 60% 61% 62% 62% 66% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a51.540858
GSM386436Untreated HCT116 cells, replicate b57.085460
GSM386437Untreated HCT116 cells, replicate d61.920463
GSM386438Untreated HCT116 cells, replicate e55.535960
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b55.489660
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d49.198157
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e46.680755
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f52.428458
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a56.098160
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b47.214155
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d51.145858
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e52.519758
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a53.75358
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c73.307867
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e51.606257
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f44.114953
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a50.274558
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c53.613460
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e52.371758
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f50.616757
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b56.053860
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c48.544256
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d48.268156
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f39.177150
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b57.089861
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c47.917456
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d59.290163
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f44.564654
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c59.372362
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d54.877659
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e58.297361
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f57.300961
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a69.186665
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b49.401656
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e56.977460
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f46.389854
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b48.944255
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c58.976660
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d52.386458
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e54.668159
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c43.950652
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d57.288460
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e53.752257
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f52.989858
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b60.090761
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d44.049752
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e59.391661
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f54.965959
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b78.112169
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c71.697966
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f58.326562
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a60.725262
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b65.338764
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d55.070859
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e61.152162
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b74.483967
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d60.110361
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a62.2662
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d57.161359
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e54.569859
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f49.526456
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a47.98656
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c55.610659
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f47.756955
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b67.725964
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e60.698563
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b62.989262
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c94.035174
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f55.205659
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c58.850660
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d59.021261
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b61.351862
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e61.826562
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f72.659366