ProfileGDS5268 / 201167_x_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 80% 81% 79% 79% 58% 75% 79% 78% 71% 86% 77% 76% 84% 46% 75% 54% 79% 85% 74% 64% 57% 76% 72% 75% 30% 53% 42% 77% 81% 81% 78% 60% 48% 82% 74% 76% 70% 76% 54% 76% 78% 68% 75% 74% 82% 85% 79% 75% 54% 39% 78% 83% 80% 71% 82% 76% 78% 76% 51% 66% 76% 62% 71% 78% 86% 44% 83% 80% 78% 87% 71% 76% 58% 69% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a157.75180
GSM386436Untreated HCT116 cells, replicate b156.73781
GSM386437Untreated HCT116 cells, replicate d139.38379
GSM386438Untreated HCT116 cells, replicate e141.07279
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b51.401858
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d111.38275
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e141.83179
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f129.47978
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a88.578971
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b257.65886
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d124.64677
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e116.37476
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a207.34684
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c37.37346
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e114.33575
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f45.262554
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a135.62579
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c242.65585
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e109.66374
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f65.884164
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b50.562357
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c118.00376
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d99.428472
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f116.90775
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b23.644430
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c43.109153
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d31.009642
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f122.17377
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c156.0681
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d149.65981
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e132.03478
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f56.448860
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a39.256648
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b182.49982
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e103.7774
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f115.77276
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b85.755270
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c109.83376
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d46.889354
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e116.97776
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c141.20178
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d78.909768
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e113.80175
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f107.44674
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b168.5182
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d221.82285
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e144.0379
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f108.29375
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b45.216954
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c30.914439
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f125.09378
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a178.33483
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b134.04380
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d87.328671
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e171.24382
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b117.44776
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d125.24478
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a121.2176
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d42.300351
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e73.461466
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f119.66576
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a59.689662
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c88.632471
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f130.51678
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b222.59486
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e34.469944
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b160.65583
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c127.91580
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f127.45978
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c234.38787
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d86.885271
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b117.08176
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e55.388158
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f81.060769