ProfileGDS5268 / 202219_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 91% 91% 92% 91% 92% 90% 90% 90% 93% 91% 91% 89% 89% 96% 90% 95% 87% 87% 90% 92% 94% 85% 86% 84% 89% 95% 91% 90% 92% 90% 91% 95% 96% 90% 92% 90% 91% 90% 93% 88% 88% 88% 91% 83% 92% 90% 91% 92% 94% 96% 91% 90% 90% 90% 92% 89% 86% 87% 93% 88% 86% 94% 95% 90% 92% 93% 92% 95% 91% 90% 89% 86% 92% 87% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a376.87991
GSM386436Untreated HCT116 cells, replicate b389.05591
GSM386437Untreated HCT116 cells, replicate d400.58192
GSM386438Untreated HCT116 cells, replicate e377.46691
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b459.96992
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d354.96390
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e383.03190
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f371.70590
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a498.01593
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b407.95791
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d383.42591
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e337.66689
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a331.17189
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c630.24496
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e371.20890
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f673.36495
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a246.14487
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c289.34487
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e381.39590
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f469.46692
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b492.3594
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c228.11585
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d269.44686
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f214.04784
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b321.14189
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c686.43195
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d387.96191
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f358.40590
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c390.43392
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d340.91890
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e386.81291
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f630.82895
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a667.83796
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b370.16990
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e418.52292
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f342.99790
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b372.61191
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c294.69490
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d474.18793
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e291.67188
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c305.37988
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d273.6288
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e367.20691
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f188.63183
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b415.92192
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d360.4190
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e395.10791
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f399.75792
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b535.07394
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c670.9996
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f351.89491
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a311.15790
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b305.91790
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d323.26390
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e408.04592
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b302.22789
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d226.04186
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a266.90287
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d415.59393
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e283.63888
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f242.02486
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a524.28494
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c605.06695
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f348.67490
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b386.90592
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e506.8593
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b386.89792
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c482.72395
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f393.71991
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c334.56290
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d273.15689
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b222.30886
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e377.05492
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f230.17687