ProfileGDS5268 / 202409_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 69% 69% 67% 69% 67% 69% 66% 67% 70% 67% 66% 64% 67% 63% 65% 66% 68% 71% 67% 75% 84% 82% 82% 80% 51% 73% 56% 69% 68% 67% 69% 72% 65% 69% 70% 67% 70% 68% 72% 70% 84% 84% 86% 81% 69% 69% 70% 67% 67% 71% 68% 72% 70% 67% 70% 71% 71% 83% 85% 79% 81% 67% 73% 67% 69% 67% 70% 70% 74% 75% 75% 79% 82% 79% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a79.252369
GSM386436Untreated HCT116 cells, replicate b80.034969
GSM386437Untreated HCT116 cells, replicate d73.121467
GSM386438Untreated HCT116 cells, replicate e80.480469
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b74.028967
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d79.554469
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e72.412366
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f75.808867
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a85.366270
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b75.92267
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d71.59566
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e66.621364
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a77.391567
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c63.064663
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e69.948565
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f69.76466
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a77.095568
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c89.440471
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e74.020567
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f114.67875
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b192.43884
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c183.11982
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d183.99682
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f156.04780
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b41.250651
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c96.252273
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d47.064556
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f78.319169
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c77.178168
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d74.784567
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e80.013769
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f92.43872
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a67.893365
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b84.161869
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e84.624570
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f75.297667
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b86.00870
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c76.942268
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d94.920572
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e83.975470
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c223.22284
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d189.54984
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e240.3686
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f162.36281
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b80.957469
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d84.616769
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e85.345670
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f75.035467
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b73.842767
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c84.139671
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f74.490468
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a94.052172
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b82.993870
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d74.287267
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e87.126270
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b87.883371
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d88.482871
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a188.60383
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d196.18485
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e138.88179
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f170.3381
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a75.412967
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c97.60873
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f74.429367
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b80.725469
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e70.536367
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b84.962770
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c80.251570
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f101.03774
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c104.3375
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d103.85275
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b138.40879
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e151.87982
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f133.9579