ProfileGDS5268 / 204337_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 33% 36% 40% 40% 37% 35% 28% 39% 40% 38% 37% 33% 35% 50% 34% 40% 42% 32% 38% 38% 38% 37% 41% 38% 46% 37% 46% 40% 40% 39% 42% 38% 39% 31% 40% 30% 35% 30% 32% 37% 32% 34% 33% 33% 34% 24% 34% 34% 42% 39% 39% 32% 38% 31% 37% 35% 25% 32% 29% 31% 34% 26% 37% 34% 41% 38% 32% 45% 33% 35% 40% 33% 37% 42% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a24.028933
GSM386436Untreated HCT116 cells, replicate b26.542536
GSM386437Untreated HCT116 cells, replicate d29.899140
GSM386438Untreated HCT116 cells, replicate e29.399440
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b27.127737
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d25.693335
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e20.822328
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f29.373539
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a30.136440
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b27.912238
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d26.897737
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e24.670433
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a25.714935
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c42.037950
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e25.203734
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f30.497640
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a31.512342
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c22.425432
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e27.723138
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f28.184838
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b28.196938
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c27.175137
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d30.439941
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f27.994438
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b36.076246
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c26.962337
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d34.681246
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f28.876540
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c30.406340
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d29.790739
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e31.633542
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f28.488438
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a30.536739
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b23.286931
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e30.079440
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f22.59530
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b27.173135
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c23.617430
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d23.887432
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e27.624537
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c23.786632
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d25.995834
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e25.415133
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f24.356133
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b25.573934
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d19.374724
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e24.93234
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f25.735134
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b32.169242
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c30.76939
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f29.196639
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a24.78932
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b28.872538
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d24.038131
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e27.828437
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b26.396235
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d20.53325
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a23.869132
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d22.984529
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e23.286931
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f25.085334
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a20.291526
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c27.878337
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f24.710634
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b31.89441
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e28.924138
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b24.997532
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c36.614645
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f25.075533
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c27.022935
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d30.662240
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b25.004733
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e29.30237
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f32.816142