ProfileGDS5268 / 205519_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 77% 78% 76% 79% 70% 80% 84% 86% 80% 84% 76% 85% 86% 56% 83% 63% 84% 84% 75% 75% 65% 76% 75% 80% 66% 67% 61% 80% 76% 75% 75% 66% 66% 76% 72% 79% 69% 75% 67% 78% 68% 69% 68% 72% 78% 80% 75% 77% 71% 67% 76% 76% 73% 69% 72% 76% 77% 70% 61% 63% 70% 71% 70% 84% 78% 65% 74% 73% 69% 68% 62% 63% 59% 61% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a124.14977
GSM386436Untreated HCT116 cells, replicate b135.60878
GSM386437Untreated HCT116 cells, replicate d115.25976
GSM386438Untreated HCT116 cells, replicate e135.55379
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b83.010170
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d155.96180
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e218.73184
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f229.83486
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a148.56480
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b209.93684
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d113.86476
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e216.34685
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a239.24786
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c50.037956
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e189.58983
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f62.202863
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a193.79884
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c232.10184
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e116.68475
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f115.21175
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b68.290165
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c120.01376
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d116.78975
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f157.28880
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b67.541866
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c73.034767
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d55.150561
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f148.46180
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c116.00376
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d109.11775
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e107.14175
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f69.179566
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a71.962466
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b119.47176
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e93.986372
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f138.62479
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b82.719869
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c108.14275
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d75.698167
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e135.18778
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c81.077268
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d82.398169
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e80.778768
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f98.371372
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b130.72678
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d158.08180
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e110.20775
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f119.22677
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b88.614671
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c71.939967
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f111.17976
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a114.16176
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b97.035773
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d80.912269
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e93.879772
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b113.64176
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d118.46177
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a87.221270
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d59.966161
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e62.977463
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f88.56670
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a87.893271
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c85.512770
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f208.50584
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b128.82378
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e66.743565
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b99.292374
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c92.209673
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f78.281669
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c79.651468
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d60.575362
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b64.241963
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e56.993459
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f59.684561