ProfileGDS5268 / 205998_x_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 77% 77% 78% 76% 77% 78% 76% 78% 79% 77% 78% 79% 76% 82% 78% 76% 77% 79% 75% 79% 80% 76% 76% 77% 78% 76% 77% 77% 78% 78% 78% 80% 79% 75% 76% 78% 76% 80% 73% 76% 77% 77% 77% 76% 77% 77% 78% 78% 80% 81% 78% 79% 80% 78% 78% 80% 80% 77% 77% 78% 78% 75% 77% 75% 80% 76% 81% 84% 77% 78% 81% 80% 80% 80% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a125.52377
GSM386436Untreated HCT116 cells, replicate b125.02677
GSM386437Untreated HCT116 cells, replicate d128.11878
GSM386438Untreated HCT116 cells, replicate e114.99876
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b122.8677
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d129.36278
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e117.72976
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f133.28778
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a138.27679
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b129.81477
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d128.26978
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e144.07279
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a118.08476
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c150.36282
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e139.02678
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f114.36576
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a122.19877
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c152.63379
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e113.0575
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f144.7379
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b144.32980
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c119.86576
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d121.75576
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f127.52577
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b121.45978
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c113.41276
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d117.86677
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f120.76177
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c129.54478
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d129.17978
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e127.5878
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f142.98280
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a131.62879
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b111.85175
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e114.97176
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f130.80578
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b114.52676
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c143.12980
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d100.93973
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e119.67876
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c129.80677
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d126.45677
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e126.73177
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f116.80376
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b124.48677
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d123.99977
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e132.29478
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f124.06678
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b142.86180
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c138.70881
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f121.03978
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a134.21679
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b134.01980
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d122.21378
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e126.5578
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b146.99480
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d146.49580
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a128.59777
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d122.91477
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e134.04478
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f135.92778
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a110.99375
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c119.41477
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f113.79975
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b137.69580
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e108.90776
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b140.25481
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c162.68784
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f118.85177
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c123.25478
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d150.17781
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b146.88280
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e141.83280
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f144.480