ProfileGDS5268 / 207673_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 29% 28% 31% 34% 35% 30% 39% 34% 39% 37% 32% 32% 30% 33% 39% 36% 31% 31% 35% 33% 29% 36% 33% 32% 32% 37% 26% 34% 33% 39% 31% 31% 32% 34% 31% 38% 39% 32% 39% 35% 33% 41% 40% 36% 36% 44% 40% 36% 34% 38% 39% 32% 34% 33% 31% 36% 33% 35% 37% 38% 34% 33% 29% 34% 38% 38% 39% 31% 28% 35% 33% 36% 40% 32% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a21.585429
GSM386436Untreated HCT116 cells, replicate b21.23228
GSM386437Untreated HCT116 cells, replicate d23.443631
GSM386438Untreated HCT116 cells, replicate e25.089834
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b25.569535
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d21.846330
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e28.379239
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f25.150134
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a29.701139
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b27.073237
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d23.717332
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e23.867732
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a22.570830
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c25.847233
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e28.99439
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f27.067136
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a22.987531
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c22.120331
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e25.445935
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f24.015433
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b22.463829
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c26.029136
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d24.501933
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f23.406732
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b24.599332
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c26.675637
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d20.661526
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f24.407534
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c24.394133
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d30.046639
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e23.10631
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f23.676531
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a25.101732
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b25.122634
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e23.55231
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f28.501838
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b29.985839
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c24.756932
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d29.685439
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e25.836335
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c24.461833
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d31.335141
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e30.602240
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f26.843336
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b27.274536
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d33.785444
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e29.548340
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f27.019136
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b25.858734
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c30.086238
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f28.981539
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a24.78932
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b25.975234
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d25.177133
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e23.686531
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b26.888236
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d25.403433
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a25.475735
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d28.525937
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e28.10438
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f25.048134
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a24.642733
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c22.587429
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f25.237834
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b29.525238
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e28.740738
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b30.990539
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c25.294331
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f21.976228
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c27.151735
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d25.382633
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b27.305436
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e31.249240
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f24.706232