ProfileGDS5268 / 207990_x_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 61% 59% 65% 59% 58% 62% 59% 59% 57% 57% 54% 58% 54% 59% 53% 62% 62% 57% 58% 56% 58% 60% 57% 57% 59% 54% 57% 57% 64% 58% 58% 58% 65% 58% 57% 57% 55% 61% 57% 57% 61% 61% 57% 56% 62% 58% 56% 59% 61% 55% 62% 60% 61% 59% 60% 59% 60% 61% 63% 57% 60% 59% 63% 57% 61% 59% 62% 64% 63% 58% 60% 61% 59% 61% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a57.901861
GSM386436Untreated HCT116 cells, replicate b54.354459
GSM386437Untreated HCT116 cells, replicate d67.171865
GSM386438Untreated HCT116 cells, replicate e53.717559
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b50.600358
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d59.013462
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e53.521759
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f54.380359
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a51.511657
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b50.643457
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d45.951854
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e53.272558
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a46.864154
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c55.0659
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e43.896553
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f60.897262
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a58.243662
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c47.853657
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e52.956558
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f49.136156
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b52.899758
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c55.417660
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d50.809857
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f50.674357
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b53.32959
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c45.013654
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d47.160157
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f48.907657
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c66.167464
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d53.953558
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e52.252958
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f52.202458
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a69.186365
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b52.524258
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e50.055357
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f51.998857
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b48.183855
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c59.283961
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d51.693757
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e51.278657
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c59.997761
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d59.651861
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e53.011957
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f49.347156
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b61.680962
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d54.643458
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e49.06956
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f54.732659
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b56.644861
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c48.778855
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f58.354362
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a57.266960
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b59.391161
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d54.936259
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e56.889960
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b55.733759
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d57.197960
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a58.856261
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d64.118463
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e51.493757
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f57.540760
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a54.583659
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c64.75163
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f50.637357
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b59.667161
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e54.150359
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b62.916662
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c67.198864
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f63.704163
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c54.377958
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d56.577860
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b60.07661
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e57.614659
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f60.042961