ProfileGDS5268 / 208586_s_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 7% 10% 5% 4% 6% 5% 6% 7% 9% 7% 7% 4% 8% 15% 6% 4% 3% 3% 6% 6% 9% 5% 3% 4% 6% 7% 5% 6% 8% 5% 8% 7% 7% 12% 8% 11% 10% 8% 9% 6% 8% 5% 10% 5% 10% 10% 8% 8% 11% 12% 5% 8% 8% 10% 7% 9% 8% 9% 10% 8% 8% 10% 11% 7% 11% 9% 9% 8% 7% 11% 10% 8% 15% 8% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a12.1167
GSM386436Untreated HCT116 cells, replicate b13.249110
GSM386437Untreated HCT116 cells, replicate d11.58925
GSM386438Untreated HCT116 cells, replicate e11.22684
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b11.71896
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d11.07095
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e11.47956
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f12.05697
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a12.86399
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b11.98387
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d12.07567
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e11.04934
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a12.39048
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c16.310515
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e11.63416
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f11.48094
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a10.67443
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c10.46673
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e11.77666
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f11.6016
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b12.88819
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c11.4025
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d10.6413
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f10.76974
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b12.0976
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c12.35837
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d11.67095
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f11.61566
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c12.55118
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d11.51645
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e12.55318
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f12.41227
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a12.44687
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b14.051212
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e12.79928
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f13.794711
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b13.412310
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c13.05728
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d12.8369
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e11.91016
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c12.40768
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d11.48165
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e13.621410
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f11.60255
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b13.403310
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d13.136510
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e12.52458
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f12.94068
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b14.066111
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c14.947412
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f11.60825
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a12.87198
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b12.77928
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d13.857510
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e12.43947
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b13.14519
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d12.65888
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a12.79369
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d13.704710
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e12.40548
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f12.34138
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a13.356610
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c14.050511
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f11.97567
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b13.768711
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e13.39399
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b13.3249
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c13.50198
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f12.40877
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c13.778911
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d13.548610
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b12.7928
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e15.874615
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f12.83548