ProfileGDS5268 / 211425_x_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 39% 34% 41% 43% 37% 36% 33% 35% 33% 31% 35% 36% 35% 46% 29% 33% 39% 32% 36% 33% 33% 35% 30% 28% 39% 31% 49% 35% 39% 37% 37% 36% 46% 40% 38% 34% 32% 42% 35% 46% 35% 34% 35% 40% 42% 36% 41% 40% 32% 41% 40% 37% 32% 34% 35% 37% 32% 33% 35% 30% 35% 36% 39% 41% 41% 35% 36% 44% 38% 34% 36% 35% 33% 35% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a28.237839
GSM386436Untreated HCT116 cells, replicate b25.165934
GSM386437Untreated HCT116 cells, replicate d30.536941
GSM386438Untreated HCT116 cells, replicate e32.056843
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b26.970237
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d25.89636
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e23.817133
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f26.22335
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a24.825933
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b23.04531
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d25.432735
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e26.83636
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a25.98735
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c36.898646
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e22.334829
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f25.421733
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a28.840139
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c22.827832
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e26.039436
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f24.447333
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b25.000833
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c25.84535
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d22.43730
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f21.186728
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b29.958239
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c22.650831
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d37.25849
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f25.445735
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c29.13839
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d28.682337
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e27.516937
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f27.035736
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a37.497846
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b30.009640
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e28.49738
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f25.629934
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b24.713732
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c33.097942
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d26.616435
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e35.790946
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c25.967435
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d25.681834
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e26.94135
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f29.718540
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b32.433942
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d27.161636
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e30.687941
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f30.232840
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b24.207832
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c33.250541
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f29.64440
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a28.343137
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b24.833532
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d26.075234
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e26.098735
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b27.632337
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d24.556632
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a24.122833
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d26.979635
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e22.45330
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f25.629235
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a26.329836
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c30.066139
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f30.523941
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b31.802341
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e26.711635
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b27.886636
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c36.145744
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f28.2938
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c25.735734
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d27.914936
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b26.309435
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e26.214933
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f26.984935