ProfileGDS5268 / 212142_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 88% 90% 89% 90% 70% 88% 90% 91% 80% 91% 88% 92% 93% 62% 89% 57% 90% 92% 83% 75% 43% 85% 85% 90% 30% 57% 51% 90% 87% 87% 87% 73% 70% 90% 82% 90% 81% 86% 62% 90% 82% 73% 78% 84% 88% 90% 90% 89% 74% 59% 90% 91% 88% 85% 89% 87% 89% 81% 34% 76% 84% 81% 73% 92% 92% 67% 89% 83% 88% 88% 85% 77% 37% 70% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a301.9988
GSM386436Untreated HCT116 cells, replicate b332.1390
GSM386437Untreated HCT116 cells, replicate d286.91489
GSM386438Untreated HCT116 cells, replicate e356.04290
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b85.567570
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d304.86588
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e374.74290
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f375.19291
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a146.19980
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b415.09691
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d295.06488
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e489.65792
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a527.76693
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c60.812762
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e330.78289
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f50.465557
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a358.21290
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c500.38892
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e199.96383
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f110.73575
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b32.518543
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c220.95185
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d248.55785
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f366.88890
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b23.588930
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c49.880857
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d40.239651
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f367.58790
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c25887
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d247.28987
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e263.77187
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f95.189873
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a83.295170
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b372.50890
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e170.12682
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f349.89490
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b149.27381
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c204.77186
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d60.381762
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e341.41590
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c192.8682
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d97.859173
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e138.54978
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f201.15984
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b262.22688
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d368.8490
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e354.15890
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f283.63689
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b100.04574
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c56.497659
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f349.46990
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a348.9291
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b261.91988
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d192.32685
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e292.05189
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b234.1787
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d277.67689
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a166.76481
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d26.542134
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e122.276
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f207.52384
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a156.03881
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c95.388873
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f454.99892
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b393.05492
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e72.833867
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b274.86989
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c147.14383
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f266.23288
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c259.98888
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d200.95185
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b120.18877
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e29.019437
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f85.684670