ProfileGDS5268 / 215026_x_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 63% 63% 61% 66% 62% 61% 61% 62% 68% 61% 64% 65% 69% 69% 68% 62% 66% 61% 65% 64% 64% 64% 65% 63% 60% 64% 55% 61% 62% 69% 60% 60% 63% 62% 61% 66% 67% 63% 69% 64% 62% 69% 67% 65% 64% 68% 65% 64% 63% 55% 65% 67% 68% 68% 67% 67% 68% 64% 69% 64% 66% 62% 71% 61% 70% 67% 69% 75% 67% 64% 66% 70% 67% 69% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a62.19263
GSM386436Untreated HCT116 cells, replicate b63.130763
GSM386437Untreated HCT116 cells, replicate d59.322161
GSM386438Untreated HCT116 cells, replicate e70.478966
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b59.936862
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d56.317161
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e58.020161
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f60.310462
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a77.112968
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b58.3861
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d64.548464
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e70.097465
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a81.944769
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c80.839769
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e79.60168
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f60.622962
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a69.02566
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c57.611861
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e66.838665
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f66.121464
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b66.979564
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c65.695664
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d69.254165
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f61.997463
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b55.980560
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c62.925564
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d45.327455
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f57.519361
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c61.057362
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d80.826769
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e56.352160
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f56.02960
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a63.514363
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b62.493862
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e58.207761
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f70.903566
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b76.551567
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c64.1363
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d79.830569
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e65.869564
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c63.914462
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d81.942769
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e79.709467
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f71.193665
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b65.645164
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d79.363868
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e67.960165
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f65.527164
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b61.341263
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c49.723555
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f66.818765
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a74.199267
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b76.710968
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d76.46268
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e73.588467
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b75.372967
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d78.762868
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a67.761564
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d82.695469
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e66.321864
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f73.734366
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a59.517462
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c89.069771
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f58.589561
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b85.29570
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e72.778667
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b81.325669
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c98.762175
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f73.687967
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c67.008964
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d70.714966
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b87.022570
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e74.785967
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f83.331169