ProfileGDS5268 / 215639_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 29% 33% 30% 29% 27% 27% 28% 32% 29% 25% 26% 32% 23% 41% 31% 38% 29% 35% 33% 29% 33% 26% 25% 28% 38% 29% 35% 30% 35% 21% 31% 30% 44% 32% 31% 26% 25% 30% 24% 25% 25% 29% 22% 26% 32% 27% 24% 28% 28% 38% 32% 30% 32% 25% 29% 27% 27% 28% 28% 27% 31% 34% 29% 27% 29% 33% 30% 41% 30% 31% 31% 30% 33% 33% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a21.586929
GSM386436Untreated HCT116 cells, replicate b24.353733
GSM386437Untreated HCT116 cells, replicate d23.065330
GSM386438Untreated HCT116 cells, replicate e21.842529
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b20.725527
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d20.65227
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e21.006828
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f23.969332
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a22.004829
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b19.455725
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d20.24826
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e24.187732
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a18.98323
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c31.999541
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e23.552231
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f28.895738
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a21.88729
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c24.354635
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e24.365433
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f21.703929
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b25.013933
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c20.317626
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d19.742525
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f21.25928
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b28.806838
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c22.01929
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d25.89635
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f22.091230
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c26.301935
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d18.22621
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e23.464631
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f23.112630
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a34.574444
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b23.950832
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e23.598931
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f20.65926
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b20.546725
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c23.299230
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d19.560424
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e20.126125
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c19.762325
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d22.247429
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e18.597622
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f20.506526
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b24.450732
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d21.176127
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e19.486824
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f21.901328
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b21.528
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c29.90438
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f23.92632
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a23.372330
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b24.318732
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d20.484125
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e22.110629
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b21.26527
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d21.558827
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a21.188928
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d22.309328
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e20.968527
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f23.358231
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a25.234634
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c22.56129
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f20.766127
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b22.651829
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e24.904733
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b23.666430
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c32.873941
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f22.877830
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c24.240831
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d23.970431
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b22.715430
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e26.217833
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f25.003133