ProfileGDS5268 / 219484_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 50% 53% 48% 41% 51% 46% 49% 48% 45% 46% 46% 45% 61% 49% 51% 53% 59% 64% 63% 59% 46% 51% 52% 55% 64% 59% 53% 48% 52% 50% 47% 46% 39% 61% 52% 55% 59% 60% 65% 62% 49% 43% 49% 54% 49% 42% 51% 47% 48% 49% 39% 53% 52% 51% 52% 68% 63% 57% 50% 51% 48% 51% 42% 47% 44% 52% 43% 41% 37% 61% 61% 49% 47% 49% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a38.959150
GSM386436Untreated HCT116 cells, replicate b43.906653
GSM386437Untreated HCT116 cells, replicate d37.457648
GSM386438Untreated HCT116 cells, replicate e30.417841
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b40.456451
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d34.632946
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e37.947749
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f38.451948
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a34.371845
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b34.73146
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d35.283446
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e34.553245
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a58.65761
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c40.869349
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e41.418451
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f44.613853
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a53.162959
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c63.22664
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e61.649663
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f54.34659
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b35.247346
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c41.088351
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d43.28552
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f46.46555
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b63.95764
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c53.002659
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d42.545653
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f36.789648
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c42.675652
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d41.186550
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e35.801447
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f35.41646
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a30.142439
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b59.554861
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e42.719252
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f48.556455
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b56.593259
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c57.047960
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d67.975165
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e60.568262
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c39.762949
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d33.10243
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e41.12649
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f46.268554
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b40.146149
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d31.760542
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e40.802251
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f36.874647
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b38.300948
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c40.652449
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f28.767439
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a44.895253
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b43.881952
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d42.233151
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e43.394952
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b77.660368
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d65.669963
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a50.727857
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d41.20550
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e41.529851
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f38.228548
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a41.739351
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c32.563842
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f36.323947
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b34.836344
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e42.527352
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b33.725743
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c33.4641
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f27.878237
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c60.643661
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d59.895961
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b40.383949
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e39.376847
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f40.355149