ProfileGDS5268 / 220148_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 20% 24% 23% 21% 30% 28% 25% 18% 24% 22% 25% 23% 20% 35% 24% 32% 24% 20% 23% 28% 25% 19% 25% 22% 42% 28% 45% 24% 34% 38% 34% 41% 37% 32% 34% 31% 24% 18% 30% 28% 21% 18% 18% 22% 22% 24% 24% 23% 33% 30% 27% 42% 41% 41% 39% 33% 38% 26% 18% 23% 18% 30% 19% 20% 28% 35% 53% 40% 60% 64% 76% 23% 27% 20% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a17.068920
GSM386436Untreated HCT116 cells, replicate b18.995724
GSM386437Untreated HCT116 cells, replicate d19.052623
GSM386438Untreated HCT116 cells, replicate e17.837121
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b22.130930
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d20.711228
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e19.267725
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f16.387818
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a19.446824
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b18.18622
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d19.568125
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e18.954123
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a17.528220
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c27.240835
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e19.609524
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f24.434132
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a19.231424
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c16.85220
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e18.818823
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f21.115228
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b20.083325
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c16.724519
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d19.597825
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f17.937922
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b32.603942
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c20.941828
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d33.315845
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f18.814924
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c25.529134
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d28.839338
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e25.202934
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f31.307441
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a28.590337
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b24.045332
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e25.265334
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f23.505431
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b19.867224
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c17.064318
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d23.077930
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e21.488428
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c17.799221
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d16.53818
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e16.9918
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f18.512522
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b18.78122
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d19.25224
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e19.055524
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f19.323323
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b24.676933
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c24.357730
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f20.746227
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a32.763342
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b31.959441
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d32.21441
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e28.913839
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b25.212133
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d28.663238
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a19.968426
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d17.042318
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e18.566223
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f16.434318
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a22.32530
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c17.601619
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f17.2420
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b21.991628
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e26.403435
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b45.385953
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c32.457640
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f56.230960
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c67.770764
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d111.46476
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b19.294423
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e22.058227
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f17.620720