ProfileGDS5268 / 220356_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 5% 9% 7% 6% 8% 11% 10% 10% 10% 10% 12% 10% 10% 15% 9% 13% 9% 17% 10% 10% 9% 11% 11% 11% 12% 9% 10% 8% 14% 16% 11% 10% 6% 13% 15% 13% 9% 16% 13% 14% 12% 12% 11% 13% 14% 9% 13% 12% 13% 10% 8% 21% 13% 17% 21% 17% 19% 21% 13% 15% 12% 12% 12% 11% 11% 15% 27% 23% 32% 28% 46% 23% 15% 25% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a11.50295
GSM386436Untreated HCT116 cells, replicate b12.91559
GSM386437Untreated HCT116 cells, replicate d12.59017
GSM386438Untreated HCT116 cells, replicate e11.84166
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b12.50958
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d13.620311
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e12.921210
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f13.106910
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a13.33310
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b13.181410
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d13.906812
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e13.071610
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a13.106310
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c16.01315
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e13.08389
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f15.019513
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a12.96229
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c15.531717
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e13.237110
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f13.075410
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b13.03229
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c13.595811
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d13.44911
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f13.697811
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b14.461312
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c13.06129
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d13.799110
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f12.51028
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c14.933214
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d15.891516
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e13.522211
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f13.494710
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a12.23946
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b14.362113
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e15.474215
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f14.669113
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b13.0149
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c16.106516
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d14.43713
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e14.861914
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c13.805912
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d14.006612
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e13.877811
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f14.584113
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b14.879914
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d12.8359
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e14.35913
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f14.443212
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b14.681613
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c13.885810
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f12.81868
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a18.283221
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b14.845413
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d16.615217
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e18.250521
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b16.213217
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d17.25919
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a17.472821
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d14.942613
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e15.060615
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f13.761612
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a13.950512
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c14.395912
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f13.396111
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b13.980311
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e15.639215
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b21.943227
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c20.401623
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f24.119232
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c22.1828
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d36.704446
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b19.311823
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e15.663215
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f20.525125