ProfileGDS5268 / 220642_x_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 84% 85% 83% 85% 85% 83% 84% 84% 84% 83% 85% 85% 82% 84% 86% 85% 85% 84% 85% 83% 81% 79% 79% 81% 85% 85% 86% 83% 83% 82% 85% 82% 81% 83% 82% 82% 82% 80% 82% 82% 79% 83% 84% 81% 83% 84% 83% 84% 85% 84% 83% 83% 81% 84% 81% 79% 80% 80% 83% 80% 81% 85% 85% 84% 82% 86% 81% 82% 82% 77% 79% 80% 79% 81% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a203.44884
GSM386436Untreated HCT116 cells, replicate b211.12485
GSM386437Untreated HCT116 cells, replicate d178.26583
GSM386438Untreated HCT116 cells, replicate e214.76585
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b211.30485
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d200.38783
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e208.01884
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f197.85484
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a204.18684
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b198.43183
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d212.58285
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e229.33285
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a181.05982
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c177.92384
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e246.71986
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f213.59585
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a216.09185
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c221.88684
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e239.53985
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f203.83283
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b154.35581
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c146.67179
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d149.64979
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f164.62881
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b201.94685
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c218.7185
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d237.7186
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f198.13483
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c178.00883
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d164.78182
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e208.96785
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f167.92982
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a149.36781
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b184.28583
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e166.24782
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f171.06682
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b168.19382
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c141.62580
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d173.65982
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e170.58482
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c155.03479
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d177.58783
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e210.04984
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f168.85181
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b182.39583
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d200.33784
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e191.70683
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f184.47984
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b195.51985
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c170.36184
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f168.62683
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a174.37983
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b148.79181
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d176.22584
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e154.79581
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b135.24779
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d143.29280
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a161.11280
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d175.98483
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e157.02680
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f170.50281
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a217.33785
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c203.46585
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f207.31984
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b164.06382
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e210.42686
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b143.99481
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c141.40482
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f156.61282
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c121.0577
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d128.99679
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b147.19380
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e128.17779
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f156.71881