ProfileGDS5268 / 222469_s_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 58% 55% 55% 57% 61% 60% 64% 58% 62% 61% 58% 61% 66% 64% 66% 62% 59% 65% 61% 64% 61% 62% 60% 59% 53% 63% 58% 60% 61% 60% 56% 60% 60% 65% 64% 58% 59% 56% 61% 60% 65% 65% 63% 59% 53% 57% 56% 53% 48% 57% 55% 59% 58% 58% 56% 60% 62% 63% 63% 61% 63% 54% 56% 52% 58% 59% 53% 54% 58% 57% 49% 58% 58% 56% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a51.969558
GSM386436Untreated HCT116 cells, replicate b47.801455
GSM386437Untreated HCT116 cells, replicate d47.001855
GSM386438Untreated HCT116 cells, replicate e50.987857
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b57.083861
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d54.257760
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e65.235264
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f53.733858
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a60.011362
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b57.430461
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d51.161858
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e59.592261
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a72.227666
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c65.901264
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e70.820266
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f60.833662
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a53.425459
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c67.5265
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e58.771261
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f66.981864
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b58.932161
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c60.662962
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d56.693760
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f54.495159
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b44.625153
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c62.089563
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d50.250558
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f55.690260
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c57.625861
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d58.382760
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e48.647756
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f55.248760
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a56.875560
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b69.871265
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e65.120364
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f53.319258
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b55.383759
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c50.006556
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d59.201961
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e57.787860
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c71.266465
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d70.532865
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e65.880263
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f54.462359
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b45.575153
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d52.574257
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e48.151356
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f44.60853
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b38.319948
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c52.380557
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f46.058755
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a54.158959
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b53.924558
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d52.847558
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e49.436256
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b58.10460
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d61.641462
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a63.63263
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d64.642763
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e59.905661
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f63.973263
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a46.126454
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c49.848356
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f42.668152
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b54.189558
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e53.233959
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b45.222553
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c48.149654
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f51.61858
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c53.082557
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d40.602749
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b53.147758
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e54.958158
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f50.840956