ProfileGDS5268 / 225660_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 29% 38% 28% 30% 32% 31% 32% 32% 32% 33% 31% 31% 37% 25% 41% 37% 39% 36% 49% 42% 47% 42% 44% 40% 30% 34% 21% 25% 28% 33% 28% 32% 30% 33% 34% 29% 40% 41% 41% 38% 45% 42% 47% 36% 33% 34% 34% 32% 29% 33% 27% 25% 22% 26% 26% 44% 32% 46% 46% 42% 49% 34% 30% 30% 29% 23% 23% 30% 22% 23% 22% 38% 45% 37% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a21.627329
GSM386436Untreated HCT116 cells, replicate b27.957438
GSM386437Untreated HCT116 cells, replicate d21.635528
GSM386438Untreated HCT116 cells, replicate e22.684130
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b23.656632
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d22.615531
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e23.664432
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f24.112832
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a23.938132
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b24.418533
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d22.785431
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e23.353531
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a27.162937
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c21.323625
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e31.008241
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f27.713737
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a28.371539
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c25.228736
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e38.099849
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f31.120742
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b36.76947
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c31.390442
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d32.758444
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f29.295840
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b23.456330
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c25.028234
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d18.296321
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f19.394725
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c21.655528
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d25.50433
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e21.450728
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f24.381432
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a23.804730
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b24.718733
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e25.29734
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f22.445929
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b31.140340
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c32.168441
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d31.274641
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e28.112938
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c35.04145
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d32.043242
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e38.702847
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f27.012736
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b24.951633
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d25.754434
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e24.899434
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f24.532332
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b22.353729
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c26.302133
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f20.792127
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a20.052625
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b18.990422
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d21.296126
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e20.803226
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b34.358444
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d24.634332
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a35.105746
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d36.95946
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e31.862942
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f39.328549
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a25.447934
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c23.514730
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f22.130430
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b22.602329
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e19.629423
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b19.446423
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c24.745330
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f18.462422
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c19.327323
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d18.971122
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b29.055838
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e36.400145
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f28.185837