ProfileGDS5268 / 226673_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 36% 32% 35% 40% 30% 31% 32% 28% 33% 34% 31% 32% 38% 29% 32% 39% 37% 33% 39% 34% 36% 31% 40% 33% 35% 27% 30% 34% 31% 32% 28% 30% 30% 31% 38% 39% 38% 31% 32% 32% 37% 39% 30% 35% 29% 33% 38% 31% 29% 28% 32% 32% 33% 28% 30% 34% 31% 41% 26% 32% 36% 34% 28% 34% 34% 30% 28% 20% 30% 37% 30% 28% 31% 28% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a25.69336
GSM386436Untreated HCT116 cells, replicate b24.135132
GSM386437Untreated HCT116 cells, replicate d26.292935
GSM386438Untreated HCT116 cells, replicate e29.528140
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b22.286830
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d22.939331
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e23.689132
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f21.581828
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a24.897933
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b24.440734
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d23.139131
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e24.307532
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a28.67138
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c23.676529
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e24.118232
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f29.490839
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a26.890537
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c23.414933
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e29.20739
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f24.771334
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b27.082636
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c22.903431
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d29.130540
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f24.303133
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b26.345235
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c20.589327
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d22.831630
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f24.524534
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c23.684431
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d24.504432
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e21.467628
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f23.014230
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a23.983830
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b23.401331
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e28.643338
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f29.309839
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b29.662838
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c24.370931
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d24.389132
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e23.928132
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c27.80537
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d29.472739
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e23.312430
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f25.816335
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b22.331429
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d24.822133
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e28.148438
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f23.713931
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b22.666829
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c22.637128
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f24.054632
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a24.188732
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b25.498833
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d22.277328
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e23.073830
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b25.629234
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d23.595231
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a30.888141
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d21.352926
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e23.949332
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f26.987236
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a24.812934
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c22.33528
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f25.234634
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b26.241234
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e22.960630
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b22.839528
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c18.655120
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f22.877830
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c28.348337
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d23.650930
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b21.732128
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e24.506631
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f21.934528