ProfileGDS5268 / 227474_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 92% 92% 92% 92% 92% 91% 92% 91% 91% 91% 91% 91% 89% 93% 90% 93% 89% 89% 88% 90% 89% 86% 85% 85% 93% 94% 93% 93% 93% 92% 92% 94% 94% 93% 93% 92% 92% 92% 92% 92% 85% 85% 85% 85% 93% 93% 93% 93% 94% 95% 93% 94% 94% 94% 94% 93% 93% 84% 88% 88% 88% 93% 93% 93% 93% 94% 94% 93% 94% 95% 95% 86% 87% 88% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a433.47292
GSM386436Untreated HCT116 cells, replicate b451.51992
GSM386437Untreated HCT116 cells, replicate d428.19292
GSM386438Untreated HCT116 cells, replicate e437.57192
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b448.21992
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d412.84391
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e473.0792
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f418.61191
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a396.93591
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b403.71991
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d404.73991
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e419.01691
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a355.58489
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c374.01493
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e386.38190
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f462.06493
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a299.95389
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c353.74589
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e318.26888
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f374.80690
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b296.20189
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c250.60586
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d237.58185
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f230.82685
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b481.68793
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c606.58494
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d518.31593
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f505.39793
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c466.40493
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d410.05992
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e451.25392
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f523.44894
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a490.10594
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b505.63493
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e481.35493
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f457.31692
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b413.30192
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c356.26792
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d443.44592
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e422.24892
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c231.75285
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d209.48685
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e220.17685
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f216.72385
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b478.43893
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d539.56393
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e480.99693
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f441.85793
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b526.98794
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c502.45695
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f517.9693
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a502.40794
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b524.53794
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d515.20894
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e551.71694
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b428.62493
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d435.10993
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a207.76484
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d263.84688
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e283.15188
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f277.07188
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a493.31393
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c483.98993
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f502.32793
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b442.69293
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e584.22394
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b485.0594
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c350.00893
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f579.71694
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c647.23295
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d586.04195
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b225.18386
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e226.27887
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f249.76588