ProfileGDS5268 / 227651_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 88% 89% 90% 90% 88% 87% 88% 87% 89% 89% 89% 88% 87% 90% 86% 90% 87% 85% 86% 90% 91% 87% 86% 85% 88% 91% 88% 89% 90% 88% 90% 91% 90% 88% 90% 89% 90% 87% 91% 88% 90% 89% 92% 88% 89% 89% 89% 89% 89% 92% 89% 89% 89% 88% 90% 89% 88% 87% 92% 87% 88% 89% 93% 88% 89% 89% 90% 92% 90% 91% 89% 86% 91% 88% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a300.66288
GSM386436Untreated HCT116 cells, replicate b308.23289
GSM386437Untreated HCT116 cells, replicate d322.86890
GSM386438Untreated HCT116 cells, replicate e349.09790
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b279.9888
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d273.08287
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e300.90388
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f267.50387
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a301.12489
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b326.41789
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d322.76589
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e283.19188
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a276.57287
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c294.41490
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e260.61486
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f351.53890
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a249.22787
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c249.74685
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e255.81986
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f380.63990
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b344.0691
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c271.3287
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d262.27386
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f236.3985
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b273.03188
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c430.38491
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d273.81188
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f333.89989
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c337.65290
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d264.15988
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e340.93390
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f378.29491
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a286.01690
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b299.71888
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e322.84190
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f300.34589
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b328.10890
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c233.96887
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d373.28491
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e297.56488
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c374.1790
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d287.88189
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e447.58292
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f292.14788
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b281.82989
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d315.0789
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e310.33689
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f301.29789
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b274.78489
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c317.62492
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f291.5389
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a273.68389
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b278.90889
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d252.79388
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e328.72290
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b300.25989
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d267.23188
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a262.94487
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d361.22492
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e264.91987
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f280.93988
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a299.76589
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c442.81493
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f290.01688
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b293.11789
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e285.29489
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b299.64390
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c314.98492
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f345.92790
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c350.49191
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d283.68389
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b229.16286
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e327.86891
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f263.53488