ProfileGDS5268 / 228113_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 38% 38% 26% 35% 37% 35% 35% 30% 40% 30% 32% 31% 27% 50% 36% 41% 32% 29% 34% 37% 50% 45% 44% 42% 34% 39% 36% 35% 30% 30% 30% 43% 44% 32% 39% 29% 31% 31% 37% 30% 55% 52% 51% 47% 31% 35% 34% 28% 36% 31% 32% 35% 33% 35% 38% 40% 32% 56% 60% 54% 53% 40% 34% 34% 32% 30% 30% 48% 36% 37% 37% 48% 68% 51% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a27.500738
GSM386436Untreated HCT116 cells, replicate b28.050138
GSM386437Untreated HCT116 cells, replicate d20.763526
GSM386438Untreated HCT116 cells, replicate e25.444135
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b27.317437
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d25.528135
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e25.256535
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f22.781130
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a30.313340
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b22.341830
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d23.640432
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e23.428931
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a20.735327
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c42.088350
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e27.178836
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f31.276741
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a23.716232
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c20.970929
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e24.884334
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f27.3237
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b39.900750
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c34.633945
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d32.802144
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f31.37442
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b26.14134
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c28.52839
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d26.443636
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f25.597535
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c23.004930
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d23.390530
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e22.784330
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f32.64843
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a34.730844
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b24.218932
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e29.054839
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f22.570929
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b24.208931
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c23.868731
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d27.935837
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e22.97230
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c47.959955
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d43.80952
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e42.993851
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f37.44147
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b23.883431
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d26.016535
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e25.342534
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f22.007828
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b26.952736
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c25.099831
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f23.9232
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a26.183335
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b25.482433
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d26.46935
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e28.195738
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b30.208840
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d24.714532
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a49.543956
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d57.914960
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e46.500754
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f44.821153
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a29.392640
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c25.659634
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f25.335534
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b24.367432
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e22.960630
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b24.002230
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c40.264548
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f27.452436
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c28.122737
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d28.363237
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b38.369948
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e79.157768
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f42.713351