ProfileGDS5268 / 228733_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 83% 86% 86% 86% 84% 82% 85% 85% 84% 85% 84% 84% 84% 92% 81% 90% 81% 82% 83% 84% 83% 78% 76% 79% 86% 89% 86% 84% 85% 81% 84% 86% 88% 84% 84% 83% 83% 83% 85% 82% 79% 78% 78% 79% 85% 86% 84% 84% 86% 88% 85% 83% 79% 84% 85% 84% 83% 81% 86% 82% 81% 86% 89% 85% 85% 87% 85% 88% 88% 86% 83% 78% 81% 79% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a197.76983
GSM386436Untreated HCT116 cells, replicate b229.31586
GSM386437Untreated HCT116 cells, replicate d225.50486
GSM386438Untreated HCT116 cells, replicate e228.77486
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b205.78784
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d182.15882
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e236.5385
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f218.07685
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a199.49984
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b230.73385
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d202.18784
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e198.99884
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a207.34584
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c348.59892
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e173.62681
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f325.56990
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a155.14981
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c183.35882
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e196.45983
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f222.25384
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b180.9983
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c136.48478
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d124.81976
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f151.63979
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b219.65986
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c340.22489
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d230.53786
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f212.99884
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c200.11285
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d157.69581
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e196.02784
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f232.34786
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a246.89188
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b214.28584
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e201.05184
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f188.34783
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b169.60583
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c167.76683
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d212.385
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e170.41282
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c153.76679
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d132.35578
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e135.17578
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f145.34979
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b215.00685
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d244.44186
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e205.63284
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f183.58584
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b212.89786
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c218.38188
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f207.19785
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a176.783
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b130.02779
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d184.40284
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e205.94685
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b186.83984
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d174.40783
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a165.10981
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d222.03786
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e171.47182
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f166.18981
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a226.72986
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c289.10889
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f221.02985
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b197.74885
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e239.14887
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b196.24985
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c216.30988
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f261.79888
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c222.8586
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d166.33383
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b129.1478
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e150.05581
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f134.00979