ProfileGDS5268 / 232803_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 9% 6% 10% 9% 11% 11% 13% 8% 7% 15% 9% 11% 15% 10% 8% 10% 15% 11% 11% 8% 8% 11% 10% 13% 8% 10% 15% 10% 9% 10% 11% 7% 4% 15% 16% 10% 8% 5% 11% 11% 8% 7% 5% 9% 6% 6% 13% 4% 9% 4% 8% 24% 13% 13% 18% 14% 16% 12% 5% 14% 12% 8% 3% 5% 9% 6% 21% 13% 29% 28% 39% 14% 8% 9% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a12.59769
GSM386436Untreated HCT116 cells, replicate b11.65546
GSM386437Untreated HCT116 cells, replicate d13.541710
GSM386438Untreated HCT116 cells, replicate e12.93329
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b13.727411
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d13.464911
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e14.076813
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f12.46358
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a12.14417
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b14.794615
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d12.87529
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e13.46811
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a15.326815
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c13.933610
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e12.39858
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f13.779410
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a15.139815
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c13.436411
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e13.730111
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f12.39168
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b12.54798
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c13.601511
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d12.96110
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f14.408313
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b13.07258
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c13.486610
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d15.43515
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f13.075410
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c13.09229
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d13.340610
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e13.73311
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f12.24987
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a11.34764
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b15.295815
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e15.688216
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f13.490310
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b12.55928
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c11.69195
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d13.892311
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e13.795711
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c12.578
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d12.0167
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e11.58325
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f13.06399
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b11.99426
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d11.84316
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e14.35913
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f11.11954
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b13.13259
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c11.59934
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f12.53578
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a19.624
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b14.721813
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d14.918113
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e16.488818
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b14.972414
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d15.940416
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a13.827412
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d11.91565
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e14.828814
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f13.696112
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a12.44078
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c11.05493
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f11.46255
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b13.1389
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e12.34826
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b18.753521
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c15.304313
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f22.173429
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c22.206128
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d30.407639
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b14.923614
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e12.70158
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f13.31849