ProfileGDS5268 / 235382_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 17% 11% 16% 18% 18% 12% 13% 9% 11% 14% 11% 11% 13% 16% 18% 21% 17% 15% 16% 17% 18% 15% 15% 15% 18% 13% 15% 10% 13% 11% 15% 12% 14% 15% 18% 11% 14% 17% 18% 17% 14% 18% 14% 13% 12% 11% 11% 14% 16% 12% 11% 16% 16% 18% 13% 22% 21% 26% 17% 18% 13% 18% 15% 12% 13% 20% 16% 13% 11% 27% 33% 24% 20% 22% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a15.690717
GSM386436Untreated HCT116 cells, replicate b13.488611
GSM386437Untreated HCT116 cells, replicate d15.723216
GSM386438Untreated HCT116 cells, replicate e16.368618
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b16.384818
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d13.819312
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e14.166513
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f12.73729
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a13.792311
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b14.611214
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d13.674111
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e13.649211
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a14.344413
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c16.697616
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e16.500718
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f18.476121
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a16.12717
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c14.789415
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e15.332116
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f15.886717
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b16.532318
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c15.026715
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d15.254715
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f15.026915
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b17.019718
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c14.247913
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d15.481115
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f13.377110
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c14.589913
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d13.725411
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e15.247615
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f14.403912
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a15.578714
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b14.999215
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e16.647318
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f13.607611
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b15.120714
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c16.655117
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d16.427718
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e16.218617
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c14.753914
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d16.680718
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e15.248614
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f14.588813
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b14.036912
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d13.412511
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e13.537411
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f15.21214
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b15.883116
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c14.77912
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f13.691311
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a16.102416
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b15.974316
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d16.862918
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e14.644513
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b18.621122
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d17.990121
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a20.332626
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d16.669917
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e16.275818
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f14.329513
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a16.443118
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c15.752715
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f13.958612
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b14.853513
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e17.772520
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b16.464516
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c15.599513
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f14.088811
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c21.7827
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d25.358733
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b19.432924
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e18.374920
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f18.908922