ProfileGDS5268 / 235481_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 6% 10% 5% 8% 8% 7% 9% 12% 7% 13% 6% 6% 6% 2% 6% 4% 6% 9% 5% 5% 5% 6% 5% 6% 4% 8% 5% 8% 6% 8% 6% 8% 14% 14% 15% 11% 14% 11% 14% 7% 15% 7% 7% 7% 14% 10% 13% 12% 4% 18% 7% 4% 6% 3% 8% 15% 7% 8% 9% 5% 9% 11% 9% 11% 6% 6% 5% 7% 3% 10% 8% 8% 9% 4% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a11.59416
GSM386436Untreated HCT116 cells, replicate b13.228810
GSM386437Untreated HCT116 cells, replicate d11.50545
GSM386438Untreated HCT116 cells, replicate e12.4618
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b12.33418
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d12.02387
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e12.78689
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f13.712612
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a12.217
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b14.340113
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d11.73476
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e11.72926
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a11.84926
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c10.51582
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e11.97656
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f11.31614
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a12.00886
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c12.69289
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e11.16135
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f11.33035
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b11.5845
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c11.516
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d11.44125
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f11.79286
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b11.54714
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c12.4368
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d11.52785
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f12.62848
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c11.80686
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d12.8228
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e11.71066
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f12.73618
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a15.255914
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b14.597814
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e15.185815
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f13.901411
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b14.930314
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c13.909911
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d14.863914
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e12.35247
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c15.051415
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d12.04887
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e12.27587
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f12.30157
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b14.991914
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d13.004810
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e14.429813
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f14.32812
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b11.15384
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c17.512618
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f12.18117
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a11.20454
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b11.82256
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d10.93783
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e12.81318
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b15.222815
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d12.39957
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a12.51818
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d13.54459
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e11.56835
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f12.84229
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a13.64311
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c13.17149
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f13.437611
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b12.11276
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e12.05596
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b11.69245
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c12.80347
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f10.95673
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c13.358510
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d12.9088
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b12.70168
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e13.22719
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f11.194