ProfileGDS5268 / 235803_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 13% 18% 8% 10% 13% 19% 16% 9% 17% 20% 19% 15% 19% 4% 11% 5% 17% 13% 16% 13% 14% 16% 22% 26% 15% 16% 21% 21% 27% 17% 34% 28% 12% 14% 15% 11% 16% 17% 9% 18% 12% 12% 11% 16% 14% 29% 25% 24% 35% 12% 36% 32% 27% 24% 17% 21% 20% 15% 7% 18% 15% 27% 24% 28% 44% 25% 51% 34% 44% 33% 73% 16% 9% 7% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a14.157513
GSM386436Untreated HCT116 cells, replicate b16.387118
GSM386437Untreated HCT116 cells, replicate d12.81878
GSM386438Untreated HCT116 cells, replicate e13.158210
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b14.525913
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d16.519919
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e15.490616
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f12.87319
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a15.93817
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b17.070120
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d16.924919
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e15.088215
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a16.92719
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c11.67654
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e13.728311
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f11.90685
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a15.921317
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c14.037813
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e15.585616
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f14.288613
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b15.075714
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c15.612116
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d17.912122
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f20.266226
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b16.046415
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c15.55216
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d18.03521
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f17.73521
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c21.326927
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d16.115117
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e25.273234
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f21.896128
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a14.632112
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b14.769314
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e15.339115
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f13.846411
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b15.989916
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c16.369917
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d13.01369
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e16.425618
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c13.91612
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d13.964212
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e13.730911
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f15.510816
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b15.059714
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d21.813729
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e19.546425
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f19.817924
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b26.19335
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c14.964412
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f26.478436
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a24.542532
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b21.263327
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d19.982924
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e16.384317
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b18.001221
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d17.530320
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a14.952515
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d12.53557
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e16.37618
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f14.995215
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a20.970827
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c19.640524
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f21.102228
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b34.96344
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e20.208325
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b43.800251
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c27.385234
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f34.213244
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c25.452933
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d96.138573
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b15.752316
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e13.41899
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f12.50457