ProfileGDS5268 / 235975_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 27% 28% 25% 25% 28% 27% 20% 24% 28% 27% 23% 25% 20% 43% 25% 28% 31% 26% 24% 23% 34% 24% 22% 20% 36% 26% 36% 31% 27% 24% 32% 28% 36% 18% 36% 22% 21% 24% 24% 21% 24% 26% 27% 23% 21% 22% 27% 22% 36% 29% 29% 34% 33% 33% 28% 25% 25% 28% 30% 19% 21% 29% 25% 26% 30% 28% 39% 44% 30% 28% 26% 29% 30% 30% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a20.223327
GSM386436Untreated HCT116 cells, replicate b21.088728
GSM386437Untreated HCT116 cells, replicate d19.896425
GSM386438Untreated HCT116 cells, replicate e19.731825
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b21.041528
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d20.674427
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e17.25520
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f19.348424
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a21.474728
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b20.464427
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d18.571623
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e19.758425
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a17.314220
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c34.228943
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e20.122125
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f21.840128
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a23.28331
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c19.539226
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e19.277124
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f18.481523
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b25.543834
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c18.95424
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d17.964222
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f17.094120
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b27.286836
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c19.938626
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d26.458136
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f22.709531
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c21.185727
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d19.796224
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e23.84132
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f21.957728
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a27.93836
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b16.598718
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e26.795636
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f18.539122
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b18.384421
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c19.767724
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d19.642724
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e17.856421
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c19.406424
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d20.625926
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e21.498127
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f19.019623
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b17.903121
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d18.170322
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e20.758327
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f18.786122
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b26.723136
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c23.725129
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f21.897929
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a25.490334
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b25.038933
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d25.367633
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e21.567428
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b20.262525
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d20.4525
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a21.29728
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d23.725130
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e17.096919
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f17.451121
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a22.138829
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c20.346125
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f19.929626
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b23.485830
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e21.962428
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b30.777139
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c35.967444
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f22.758830
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c22.281728
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d21.064726
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b22.458629
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e23.99330
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f23.002230